Skip Navigation

At Oerth Bio, we are on a mission to change perceptions of agricultural chemistry

We are leading a new and transformative approach to crop protection, crop health and healthy food by leveraging our proprietary PROTAC® protein degraders, or proteolysis-targeting chimeras. PROTAC protein degraders work by harnessing the plant's own natural protein disposal system to degrade and remove unwanted proteins. We are an early-stage agriculture biotechnology company located in the heart of downtown Durham, North Carolina.

Revolutionizing the food system and improving human health

We are working to unlock the full potential of PROTAC protein degradation by developing our own robust pipeline and by partnering with the world’s leading agricultural and food companies.

Founded by leaders in life sciences

Leaps by Bayer

Leaps by Bayer is spearheading a movement to make paradigm-shifting advances in the life sciences – targeting the breakthroughs that could fundamentally change the world for the better.


Arvinas is a clinical-stage biopharmaceutical company leading the creation of an entirely new way to treat disease through therapies that target and degrade disease-related proteins.

“This alliance is a unique combination of expertise to truly shape the future of agriculture. The work that will be done by Oerth Bio could help farmers overcome the diseases, pests, and weeds that lead to lost crop yields every year.”

– Bob Reiter, Head of R&D, Crop Science division of Bayer