Our Attune™ Platform

Attune™ is our proprietary R&D platform for developing solutions that solve longstanding agricultural issues and address new ones as they emerge, without changing the plant genome.

The Attune platform harnesses and ignites a natural biological system existing within all animals, plants, insects, and fungi—a system responsible for regulating cellular harmony. Attune is targeting, modulating, and tuning this system for specific outcomes to help crops thrive in the face of disease, pest, and climate pressures. All this without affecting plant DNA and without causing negative environmental or biome effects, off-target responses, or cross-species impacts.

There's never been a safer way to:

Protect crops from weeds and invasive species, pests, fungi, and other threats—without harming the surrounding environment.
Increase plant resilience through enhanced immunity, stronger root structures and density, and maximized fertilizer use to better handle harsh environmental conditions.
Improve taste, appearance, nutritional value, and post-harvest efficiency of crops without altering the plant genome.

Attune

Attune integrates three key pillars of the protein modulation process for developing a precise, tunable, agricultural solution.

Ligase Selection & Ligand Identification

Our robust library of E3 ligases, linkers, and ligands enables us to conduct virtual and high-throughput screening of specific plants and pests. This is a key step in matching a specific ligase with a specific target, ensuring specificity to avoid cross plant or cross-species effects.

Rapid PROTAC® Molecule Design

We use cheminformatics and molecular modeling to rapidly design PROTAC molecules for a particular target to address an agricultural need.

Agricultural Validation

We use state-of-the-art chemistry, biological characterization, and screening to optimize our PROTAC molecules for formulation, efficacy, and selectivity in multiple plants, disease, and insect systems.